Extracellular vesicles (EVs) are considered essential biomarkers in liquid biopsies.Despite intensive efforts aimed at employing EVs in a clinical setting, workable approaches are currently limited owing to the fact that EV-isolation technologies are still in a nascent stage.This study introduces a magnetic bead-based ion exchange platform for isol
Impact of Glycemic Control on Coronary Inflammation Evaluated by Computed Tomography Pericoronary Fat Attenuation Index in Patients with Acute Coronary Syndrome
Background: Coronary inflammation causes significantly increased risk of cardiovascular disease (CVD) in diabetic patients.This study investigated the relationship between coronary local inflammation, detected by pericoronary fat attenuation index (FAI), and different blood glucose control levels in low-risk acute coronary syndrome (ACS) patients w
An Unusual Metastasis of a Transglottic Squamous Cell Carcinoma to the Forearm
Introduction.Each year around 2,200 people in the UK are diagnosed with laryngeal SCC (Office of National Statistics 2009).Compared to pharyngeal carcinoma, it is a highly curable disease with a survival rate of around 60% for all stages and all forms of treatment.Case Presentation.We present the case of a 60-year-old man with a previously treated
Retinoblastoma: An update on genetic origin, classification, conventional to next-generation treatment strategies
The most prevalent paediatric vision-threatening medical condition, retinoblastoma (RB), has been a global concern for a DSLR Lens long time.Several conventional therapies, such as systemic chemotherapy and focal therapy, have been used for curative purposes; however, the search for tumour eradication with the least impact on surrounding tissues is